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  • Synthetic lifeform created for first time-amazing.

    Incredible stuff. The video the page links to has an interview with Craig Venter who led the team. Mindblowing.

    http://www.youtube.com/v/47rUrlzdK3k... height="344">


    From here

    Scientists have created the world's first synthetic life form in a landmark experiment that paves the way for designer organisms that are built rather than evolved.
    The controversial feat, which has occupied 20 scientists for more than 10 years at an estimated cost of $40m, was described by one researcher as "a defining moment in biology".
    Craig Venter, the pioneering US geneticist behind the experiment, said the achievement heralds the dawn of a new era in which new life is made to benefit humanity, starting with bacteria that churn out biofuels, soak up carbon dioxide from the atmosphere and even manufacture vaccines.
    However critics, including some religious groups, condemned the work, with one organisation warning that artificial organisms could escape into the wild and cause environmental havoc or be turned into biological weapons. Others said Venter was playing God.
    The new organism is based on an existing bacterium that causes mastitis in goats, but at its core is an entirely synthetic genome that was constructed from chemicals in the laboratory.
    The single-celled organism has four "watermarks" written into its DNA to identify it as synthetic and help trace its descendants back to their creator, should they go astray.
    "We were ecstatic when the cells booted up with all the watermarks in place," Dr Venter told the Guardian. "It's a living species now, part of our planet's inventory of life."
    Dr Venter's team developed a new code based on the four letters of the genetic code, G, T, C and A, that allowed them to draw on the whole alphabet, numbers and punctuation marks to write the watermarks. Anyone who cracks the code is invited to email an address written into the DNA.
    The research is reported online today in the journal Science.
    "This is an important step both scientifically and philosophically," Dr Venter told the journal. "It has certainly changed my views of definitions of life and how life works."
    The team now plans to use the synthetic organism to work out the minimum number of genes needed for life to exist. From this, new microorganisms could be made by bolting on additional genes to produce useful chemicals, break down pollutants, or produce proteins for use in vaccines.
    Julian Savulescu, professor of practical ethics at Oxford University, said: "Venter is creaking open the most profound door in humanity's history, potentially peeking into its destiny. He is not merely copying life artificially ... or modifying it radically by genetic engineering. He is going towards the role of a god: creating artificial life that could never have existed naturally."
    This is "a defining moment in the history of biology and biotechnology", Mark Bedau, a philosopher at Reed College in Portland, Oregon, told Science.
    Dr Venter became a controversial figure in the 1990s when he pitted his former company, Celera Genomics, against the publicly funded effort to sequence the human genome, the Human Genome Project. Venter had already applied for patents on more than 300 genes, raising concerns that the company might claim intellectual rights to the building blocks of life.

  • #2
    Re: Synthetic lifeform created for first time-amazing.

    Cool.

    Here we are worried about the Internet gaining control over us, and someone else is already synthesizing new life forms from human designed DNA sequences.
    Most folks are good; a few aren't.

    Comment


    • #3
      Re: Synthetic lifeform created for first time-amazing.

      sounds like that venter guy has a massive God complex. be afraid, be very afraid.

      Comment


      • #4
        Re: Synthetic lifeform created for first time-amazing.

        Originally posted by ThePythonicCow View Post
        Cool.
        I am horrified

        Comment


        • #5
          Re: Synthetic lifeform created for first time-amazing.

          Venter is pretty out there

          Still, nothing to be afraid of. That thing is just a very simple machine built from chemicals. It's only 'alive' because those chemicals happen to be carbon molecules and DNA

          Comment


          • #6
            Re: Synthetic lifeform created for first time-amazing.

            Originally posted by Ben View Post
            Venter is pretty out there

            Still, nothing to be afraid of. That thing is just a very simple machine built from chemicals. It's only 'alive' because those chemicals happen to be carbon molecules and DNA
            I would beg to differ with you. It is a self replicating machine, and it is unknown how long lived it is, and whether its interactions with other organisms are benign or toxic. While it may currently be "contained" in the lab, its impacts on the web of life are undetermined. This approach cannot be compared with natural mutation. There are typically many more safeguards in nature to deal with normal mutation than there appear to be here. This is primarily because the mutated organism starts as a single unit, and has no protection from the surrounding organisms, as is being afforded to this organism in the lab.

            Comment


            • #7
              Re: Synthetic lifeform created for first time-amazing.

              What has me very worried is this guys interet in patents. Privatising this kind of technology is just crazy, my mind goes to all sorts of horrible places thinking about the kind of power that certain individuals will have over the conditons and choices available to the rest of us.

              Comment


              • #8
                Re: Synthetic lifeform created for first time-amazing.

                I am horrified
                Brace yourself, this is but the beginning. At any given point, mankind's technological grasp almost always exceeds his intellectual, moral, and ethical reach. Up until now, one might argue, it has been mostly advantageous overall. It will probably continue to be advantageous ... until it isn't.

                Rajiv, I share your concern.

                Comment


                • #9
                  Re: Synthetic lifeform created for first time-amazing.

                  Originally posted by Rajiv View Post
                  I would beg to differ with you. It is a self replicating machine, and it is unknown how long lived it is, and whether its interactions with other organisms are benign or toxic. While it may currently be "contained" in the lab, its impacts on the web of life are undetermined. This approach cannot be compared with natural mutation. There are typically many more safeguards in nature to deal with normal mutation than there appear to be here. This is primarily because the mutated organism starts as a single unit, and has no protection from the surrounding organisms, as is being afforded to this organism in the lab.
                  The same can be said for GMO crops which, because they were derived from familiar plants, seem somehow at least to some people to be safer. Of course, they seem to be safest to those who profit from them and those who get paid off by their producers. Your argument applies much more to GMO crops and their effects on the biosphere than to artificial organisms that today can only survive in specific artificial conditions that do not occur naturally.

                  However, that said, give the artificial life folks some time and the gray goo fears of nanotechnology may first be created by artificial life forms.

                  Comment


                  • #10
                    Re: Synthetic lifeform created for first time-amazing.

                    Back in the day in the 1800's when they mined coal, alot of men died from the horrible conditions and low light levels, then some guy managed to create a lamp that could be used in coal mines and not blow up in the methane gases. Everyone thought this would be the greatest thing ever in coal mining. Since then more people have died in coal mining then before the invention. In fact deaths immediately skyrocketed, since the men mined longer and deeper. All the light did was expand the coal mining industry and more deaths.

                    This could be another one of these 'things' where humans 'outsmart' themselves.

                    Comment


                    • #11
                      Re: Synthetic lifeform created for first time-amazing.

                      Originally posted by Rajiv View Post
                      I would beg to differ with you. It is a self replicating machine, and it is unknown how long lived it is, and whether its interactions with other organisms are benign or toxic. While it may currently be "contained" in the lab, its impacts on the web of life are undetermined. This approach cannot be compared with natural mutation. There are typically many more safeguards in nature to deal with normal mutation than there appear to be here. This is primarily because the mutated organism starts as a single unit, and has no protection from the surrounding organisms, as is being afforded to this organism in the lab.
                      Very true, and scary. Nature also has its own self destruct mechanisms, from infertility, diseases, and diformities.

                      Comment


                      • #12
                        Re: Synthetic lifeform created for first time-amazing.

                        Originally posted by chr5648 View Post
                        Very true, and scary. Nature also has its own self destruct mechanisms, from infertility, diseases, and deformities.
                        As my son came to know his powers in the world, I did not try to isolate him from cars, women, booze, the web, money, debt, ... Rather I tried to teach him understanding, morality and responsibility.

                        I view this first replicated cell using human designed DNA as I viewed the Altair 8800 on the January 1975 cover of Popular Electronics:


                        Both good and evil will flow from this, possibly much of both. It is our duty to teach those who come after us understanding, morality and responsibility.

                        Stand athwart history yelling Stop if you like (apologies to William F. Buckley, Jr.) but that would be to little avail. There is immense and new power here; embrace it and learn it well. It may be that humankind is not yet worthy of such power, but that is not for us to determine. We each individually can only do our best to be worthy ourselves and to guide others thusly.
                        Most folks are good; a few aren't.

                        Comment


                        • #13
                          Re: Synthetic lifeform created for first time-amazing.

                          If you haven't read it yet, I suggest reading Bill Joy's "Why The Future Doesn't Need Us", April 2000.

                          Bill Joy, co-founder and Chief Scientist of Sun Microsystems, was co-chair of the presidential commission on the future of IT research, and is co-author of The Java Language Specification.
                          The greatest obstacle to discovery is not ignorance - it is the illusion of knowledge ~D Boorstin

                          Comment


                          • #14
                            Re: Synthetic lifeform created for first time-amazing.

                            If you haven't read it yet, I suggest reading Bill Joy's "Why The Future Doesn't Need Us", April 2000.
                            Well, I will confess to doubting Bill Joy since I first had occasion to hack his editor (vi) and shell (csh) code, some 30 years ago. To this day, I avoid using vi or csh. My (now fading) recollection is that his code was crap. Certainly his "interface" design talents were not put on their best display in these tools. See for example Tom Christiansen's "Csh Programming Considered Harmful". Tom is less of a diplomat than I. See also Bruce Barnett's "Top Ten Reasons not to use the C shell".

                            Bill Joy's talents (fast hacking of code that does new things, even if not very pretty code) and good fortune (at being in Sun Microsystems from its beginning) have provided him with a platform to speak to the "big issues" of the day which few of us can command. But his comments are less than brilliant derivatives of Kurzweil's and others works.

                            Kurzweil is a "futurist" noted for his prediction of a technological singularity. I predict that that prediction is entirely wrong. As always has been through the advancement of human civilization and as will continue to be for a long time to come, such advances in technology may serve to help us better understand our own human complexity, but they will not threaten our species dominance in the slightest (unless perhaps we use such tools as nuclear bombs or biological warfare to destroy civilization ourselves.)
                            Most folks are good; a few aren't.

                            Comment


                            • #15
                              Re: Synthetic lifeform created for first time-amazing.

                              Originally posted by ThePythonicCow View Post
                              Well, I will confess to doubting Bill Joy since I first had occasion to hack his editor (vi) and shell (csh) code, some 30 years ago. To this day, I avoid using vi or csh. My (now fading) recollection is that his code was crap. Certainly his "interface" design talents were not put on their best display in these tools. See for example Tom Christiansen's "Csh Programming Considered Harmful". Tom is less of a diplomat than I. See also Bruce Barnett's "Top Ten Reasons not to use the C shell".

                              Bill Joy's talents (fast hacking of code that does new things, even if not very pretty code) and good fortune (at being in Sun Microsystems from its beginning) have provided him with a platform to speak to the "big issues" of the day which few of us can command. But his comments are less than brilliant derivatives of Kurzweil's and others works.

                              Kurzweil is a "futurist" noted for his prediction of a technological singularity. I predict that that prediction is entirely wrong. As always has been through the advancement of human civilization and as will continue to be for a long time to come, such advances in technology may serve to help us better understand our own human complexity, but they will not threaten our species dominance in the slightest (unless perhaps we use such tools as nuclear bombs or biological warfare to destroy civilization ourselves.)
                              In general, I agree with all of your comments on Joy and Kurweil's singularity. I believe the narratives were published for their propaganda value, but that is an entirely different conversation that is not consistent with this thread topic and is way outside the comfort zone of this forum. In any event, I submitted Joy's article because it's germane to the original post in this thread, and gives readers some additional food for thought.
                              The greatest obstacle to discovery is not ignorance - it is the illusion of knowledge ~D Boorstin

                              Comment

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